SIN3B anticorps (Middle Region)

N° du produit ABIN928396

Détail du produit anti-SIN3B anticorps

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3B est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Boeuf (Vache), Grenouille, Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: SIN3 B antibody was raised in rabbit using the middle region of SIN3 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

SIN3B Blocking Peptide, catalog no. 33R-5540, is also available for use as a blocking control in assays to test for specificity of this SIN3B antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur SIN3B

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Autre désignation: SIN3B (SIN3B Produits)

Synonymes: anticorps fj63d08, anticorps si:dkey-6n6.6, anticorps wu:fj63d08, anticorps 2810430C10Rik, anticorps SIN3 transcription regulator family member B, anticorps SIN3 transcription regulator family member B S homeolog, anticorps transcriptional regulator, SIN3B (yeast), anticorps sin3b, anticorps SIN3B, anticorps sin3b.S, anticorps Sin3b

Sujet: SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription. Synonyms: Polyclonal SIN3B antibody, Anti-SIN3B antibody, SIN3 homolog B, transcription regulator, yeast antibody, KIAA0700 antibody.