PYHIN1 anticorps (N-Term)

N° du produit ABIN928476

Détail du produit anti-PYHIN1 anticorps

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYHIN1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Chien

Purification: Purified

Immunogène: PYHIN1 antibody was raised in rabbit using the N terminal of PYHIN1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PYHIN1 Blocking Peptide, catalog no. 33R-1404, is also available for use as a blocking control in assays to test for specificity of this PYHIN1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PYHIN1

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Autre désignation: PYHIN1 (PYHIN1 Produits)

Synonymes: anticorps IFIX, anticorps RP11-520H16.1, anticorps 4930422C14, anticorps AI447904, anticorps Ifi209, anticorps Ifix, anticorps pyrin and HIN domain family member 1, anticorps interferon activated gene 209, anticorps PYHIN1, anticorps Ifi209

Sujet: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. Synonyms: Polyclonal PYHIN1 antibody, Anti-PYHIN1 antibody, pyrin and HIN domain family, member 1 antibody, IFIX antibody, MGC23885 antibody, RP11-520H16.1 antibody.