MBNL2 anticorps (Middle Region)

N° du produit ABIN928546

Détail du produit anti-MBNL2 anticorps

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Chien, Poulet, Boeuf (Vache), Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: MBNL2 antibody was raised in rabbit using the middle region of MBNL2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

MBNL2 Blocking Peptide, catalog no. 33R-2607, is also available for use as a blocking control in assays to test for specificity of this MBNL2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur MBNL2

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Autre désignation: MBNL2 (MBNL2 Produits)

Synonymes: anticorps 1110002M11Rik, anticorps AI047808, anticorps AI837313, anticorps AI849185, anticorps AL118326, anticorps MBLL, anticorps R75232, anticorps mKIAA4072, anticorps wu:fj89c04, anticorps MBLL39, anticorps PRO2032, anticorps muscleblind like splicing factor 2, anticorps muscleblind-like splicing regulator 2, anticorps muscleblind like splicing regulator 2, anticorps Mbnl2, anticorps mbnl2, anticorps MBNL2

Sujet: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM). Synonyms: Polyclonal MBNL2 antibody, Anti-MBNL2 antibody, muscleblind-like 2, Drosophila antibody, DKFZp781H1296 antibody, MBLL antibody, MBLL39 antibody, MGC120625 antibody, MGC120626 antibody, MGC120628 antibody, PRO2032 antibody.