PAXIP1 anticorps (N-Term)

N° du produit ABIN928548

Détail du produit anti-PAXIP1 anticorps

Antigène: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAXIP1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Chien, Grenouille, Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: PAXIP1 antibody was raised in rabbit using the N terminal of PAXIP1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PAXIP1 Blocking Peptide, catalog no. 33R-5988, is also available for use as a blocking control in assays to test for specificity of this PAXIP1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PAXIP1

Antigène: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Autre désignation: PAXIP1 (PAXIP1 Produits)

Synonymes: anticorps CAGF29, anticorps PACIP1, anticorps PAXIP1L, anticorps PTIP, anticorps TNRC2, anticorps wu:fa04b06, anticorps zgc:92593, anticorps cagf28, anticorps cagf29, anticorps k14, anticorps pacip1, anticorps paxip1l, anticorps ptip, anticorps tnrc2, anticorps D5Ertd149e, anticorps PAX interacting protein 1, anticorps PAX interacting (with transcription-activation domain) protein 1, anticorps PAX interacting protein 1 L homeolog, anticorps PAXIP1, anticorps paxip1, anticorps paxip1.L, anticorps Paxip1

Sujet: PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation. Synonyms: Polyclonal PAXIP1 antibody, Anti-PAXIP1 antibody, PAX interacting, with transcription-activation domain protein 1 antibody, PTIP antibody, TNRC2 antibody, CAGF28 antibody, CAGF29 antibody, PACIP1 antibody, PAXIP1L antibody, FLJ41049 antibody.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response