Mre11 anticorps (Middle Region)
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- Antigène Voir toutes Mre11 (MRE11A) Anticorps
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Mre11 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogène
- MRE11 A antibody was raised in rabbit using the middle region of MRE11 as the immunogen
- Top Product
- Discover our top product MRE11A Anticorps primaire
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- Indications d'application
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Commentaires
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MRE11A Blocking Peptide, catalog no. 33R-7907, is also available for use as a blocking control in assays to test for specificity of this MRE11A antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Antigène
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Autre désignation
- MRE11A (MRE11A Produits)
- Synonymes
- anticorps wu:faa63d12, anticorps zgc:64018, anticorps Mre11, anticorps Mre11b, anticorps ATLD, anticorps HNGS1, anticorps MRE11, anticorps MRE11B, anticorps MRE11 homolog A, double strand break repair nuclease, anticorps MRE11 homolog, double strand break repair nuclease, anticorps MRE11A homolog A, double strand break repair nuclease, anticorps mre11a, anticorps MRE11, anticorps Mre11a
- Sujet
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. Synonyms: Polyclonal MRE11A antibody, Anti-MRE11A antibody, MRE11 meiotic recombination 11 homolog A, S. cerevisiae antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody.
- Pathways
- Réparation de l'ADN
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