USP10 anticorps (C-Term)

N° du produit ABIN929190

Détail du produit anti-USP10 anticorps

Antigène: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Épitope: C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP10 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat (Rattus)

Purification: Purified

Immunogène: Usp10 antibody was raised in rabbit using the C terminal of Usp10 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

Usp10 Blocking Peptide, catalog no. 33R-7850, is also available for use as a blocking control in assays to test for specificity of this Usp10 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur USP10

Antigène: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Autre désignation: Usp10 (USP10 Produits)

Synonymes: anticorps T4F9.30, anticorps T4F9_30, anticorps ubiquitin-specific protease 9, anticorps ubpo, anticorps USP10, anticorps id:ibd1190, anticorps wu:fc19h08, anticorps wu:fc76g05, anticorps wu:fi11g01, anticorps UBPO, anticorps 2610014N07Rik, anticorps Uchrp, anticorps mKIAA0190, anticorps usp10-A, anticorps ubiquitin specific peptidase 10, anticorps universal stress protein UspA, anticorps ubiquitin-specific protease 9, anticorps ubiquitin carboxyl-terminal hydrolase 10, anticorps ubiquitin specific peptidase 10 S homeolog, anticorps USP10, anticorps RR_RS14970, anticorps UBP9, anticorps PTRG_07201, anticorps MGYG_06403, anticorps usp10, anticorps Usp10, anticorps usp10.S

Sujet: Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling. Synonyms: Polyclonal Usp10 antibody, Anti-Usp10 antibody, ubiquitin specific peptidase 10 antibody, MGC124997 antibody.