Factor VII anticorps (C-Term)

N° du produit ABIN929426

Détail du produit anti-Factor VII anticorps

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor VII est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: F7 antibody was raised in rabbit using the C terminal of F7 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

F7 Blocking Peptide, catalog no. 33R-1026, is also available for use as a blocking control in assays to test for specificity of this F7 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Factor VII

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Autre désignation: F7 (F7 Produits)

Synonymes: anticorps F7, anticorps wu:fb59f04, anticorps zgc:109870, anticorps SPCA, anticorps AI114908, anticorps ATIII, anticorps At-3, anticorps At3, anticorps LOC100223776, anticorps AI132620, anticorps Cf7, anticorps FVII, anticorps mfVII, anticorps f7, anticorps coagulation factor VII, anticorps serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1, anticorps coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog, anticorps F7, anticorps f7, anticorps Serpinc1, anticorps CpipJ_CPIJ009142, anticorps CpipJ_CPIJ010295, anticorps CpipJ_CPIJ020127, anticorps fa7, anticorps f7.S

Sujet: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. Synonyms: Polyclonal F7 antibody, Anti-F7 antibody, coagulation factor VII, serum prothrombin conversion accelerator antibody.

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling