E2F6 anticorps

N° du produit ABIN930975

Détail du produit anti-E2F6 anticorps

Antigène: E2F6 (E2F Transcription Factor 6 (E2F6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp E2F6 est non-conjugé

Application: Immunocytochemistry (ICC), Dot Blot (DB)

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: E2 F6 antibody was raised in mouse using recombinant Human E2 Transcription Factor 6, Transcript Variant A

Clone: E2F6B9E2

Isotype: IgG1

Information d'application

Indications d'application: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: E2 F6 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur E2F6

Antigène: E2F6 (E2F Transcription Factor 6 (E2F6))

Autre désignation: E2F6 (E2F6 Produits)

Synonymes: anticorps E2F-6, anticorps AI462434, anticorps E2F6b, anticorps EMA, anticorps E2F transcription factor 6, anticorps E2F6, anticorps E2f6

Sujet: This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Synonyms: Monoclonal E2F6 antibody, Anti-E2F6 antibody, E2F transcription factor 6 antibody, E2F-6 antibody.