C14orf169 + NO66 anticorps

N° du produit ABIN931094

Détail du produit anti-C14orf169 + NO66 anticorps

Antigène: C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C14orf169 + NO66 est non-conjugé

Application: Dot Blot (DB)

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: C14 orf169 antibody was raised in mouse using recombinant Human Chromosome 14 Open Reading Frame 169 (C14 rf169)

Clone: 3354C5a

Isotype: IgG1

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: C14 orf169 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur C14orf169 + NO66

Antigène: C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

Autre désignation: C14orf169 (C14orf169 Produits)

Synonymes: anticorps LOC453015, anticorps C10H14orf169, anticorps MAPJD, anticorps NO66, anticorps ROX, anticorps C14orf169, anticorps No66, anticorps im:7141580, anticorps no66, anticorps chromosome 14 open reading frame 169, anticorps ribosomal oxygenase 1, anticorps chromosome 5 open reading frame, human C14orf169, anticorps LOC453015, anticorps Bm1_08415, anticorps RIOX1, anticorps C5H14ORF169, anticorps Riox1, anticorps riox1

Sujet: C14orf169 encodes a histone demethylase that specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys 36' (H3K36me2). It also acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Synonyms: Monoclonal C14orf169 antibody, Anti-C14orf169 antibody, Chromosome 14 open reading frame 169 antibody, FLJ21802 antibody.