CBFB anticorps

N° du produit ABIN931127

Détail du produit anti-CBFB anticorps

Antigène: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBFB est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Dot Blot (DB)

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: CBFB antibody was raised in mouse using recombinant Human Core-Binding Factor, Beta Subunit

Clone: 344C3a

Isotype: IgG1

Information d'application

Indications d'application: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: CBFB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur CBFB

Antigène: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Autre désignation: CBFB (CBFB Produits)

Synonymes: anticorps PEBP2B, anticorps Cbfb, anticorps pebp2b, anticorps Pebp2, anticorps CBFB, anticorps unp1266, anticorps cbf-beta, anticorps cbfbeta, anticorps pea2-beta, anticorps pebp2-beta, anticorps AI893578, anticorps PEA2, anticorps PEBP2b, anticorps Pebpb2, anticorps core-binding factor beta subunit, anticorps core binding factor beta subunit, anticorps core-binding factor, beta subunit, anticorps core-binding factor, beta subunit S homeolog, anticorps core binding factor beta, anticorps CBFB, anticorps Cbfb, anticorps cbfb, anticorps cbfb.S

Sujet: The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Synonyms: Monoclonal CBFB antibody, Anti-CBFB antibody, Core-binding factor subunit beta antibody, PEBP2B antibody.

Pathways: Regulation of Lipid Metabolism by PPARalpha