CTCF anticorps
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- Antigène Voir toutes CTCF Anticorps
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CTCF est non-conjugé
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Application
- Immunocytochemistry (ICC), Dot Blot (DB)
- Réactivité croisée
- Humain
- Réactivité croisée (Details)
- Other species not studied.
- Purification
- Protein G affinity chromatography
- Immunogène
- CTCF antibody was raised in mouse using recombinant Human Ccctc-Binding Factor (Zinc Finger Protein)
- Clone
- 252C3a
- Isotype
- IgG1
- Top Product
- Discover our top product CTCF Anticorps primaire
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- Indications d'application
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ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- CTCF antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- Antigène
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
- Autre désignation
- CTCF (CTCF Produits)
- Synonymes
- anticorps im:7152666, anticorps CTCF, anticorps xctcf, anticorps AW108038, anticorps CCCTC-binding factor, anticorps CCCTC-binding factor (zinc finger protein), anticorps CTCF, anticorps ctcf, anticorps Ctcf
- Sujet
- This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Synonyms: Monoclonal CTCF antibody, Anti-CTCF antibody, CCCTC-binding factor (zinc finger protein) antibody.
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