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TFEB anticorps

TFEB Reactivité: Humain WB, DB Hôte: Souris Monoclonal 319C2a unconjugated
N° du produit ABIN931190
  • Antigène Voir toutes TFEB Anticorps
    TFEB (Transcription Factor EB (TFEB))
    Reactivité
    • 62
    • 30
    • 26
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 55
    • 6
    • 1
    Souris
    Clonalité
    • 56
    • 5
    Monoclonal
    Conjugué
    • 38
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TFEB est non-conjugé
    Application
    • 56
    • 32
    • 14
    • 13
    • 13
    • 11
    • 10
    • 8
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), Dot Blot (DB)
     Réactivité croisée
    Humain
    Réactivité croisée (Details)
    Other species not studied.
    Purification
    Protein G affinity chromatography
    Immunogène
    TFEB antibody was raised in mouse using recombinant Human Transcription Factor Eb (Tfeb)
    Clone
    319C2a
    Isotype
    IgG1
    Top Product
    Discover our top product TFEB Anticorps primaire
  • Indications d'application
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    TFEB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • Antigène
    TFEB (Transcription Factor EB (TFEB))
    Autre désignation
    TFEB (TFEB Produits)
    Synonymes
    anticorps TFEB, anticorps tcfeb, anticorps MGC145796, anticorps alphatfeb, anticorps ALPHATFEB, anticorps BHLHE35, anticorps TCFEB, anticorps Tcfeb, anticorps bHLHe35, anticorps transcription factor EB, anticorps TFEB, anticorps tfeb, anticorps Tfeb
    Sujet
    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. Synonyms: Monoclonal TFEB antibody, Anti-TFEB antibody, Transcription factor EB antibody, TCFEB antibody, AlphaT antibody.
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