TFEB anticorps
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- Antigène Voir toutes TFEB Anticorps
- TFEB (Transcription Factor EB (TFEB))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TFEB est non-conjugé
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Application
- Western Blotting (WB), Dot Blot (DB)
- Réactivité croisée
- Humain
- Réactivité croisée (Details)
- Other species not studied.
- Purification
- Protein G affinity chromatography
- Immunogène
- TFEB antibody was raised in mouse using recombinant Human Transcription Factor Eb (Tfeb)
- Clone
- 319C2a
- Isotype
- IgG1
- Top Product
- Discover our top product TFEB Anticorps primaire
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- Indications d'application
- Optimal conditions should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- TFEB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- Antigène
- TFEB (Transcription Factor EB (TFEB))
- Autre désignation
- TFEB (TFEB Produits)
- Synonymes
- anticorps TFEB, anticorps tcfeb, anticorps MGC145796, anticorps alphatfeb, anticorps ALPHATFEB, anticorps BHLHE35, anticorps TCFEB, anticorps Tcfeb, anticorps bHLHe35, anticorps transcription factor EB, anticorps TFEB, anticorps tfeb, anticorps Tfeb
- Sujet
- Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. Synonyms: Monoclonal TFEB antibody, Anti-TFEB antibody, Transcription factor EB antibody, TCFEB antibody, AlphaT antibody.
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