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alpha Fetoprotein anticorps

AFP Reactivité: Humain WB, ELISA, IP, ICC Hôte: Souris Monoclonal AFP-01 unconjugated
N° du produit ABIN93889
  • Antigène Voir toutes alpha Fetoprotein (AFP) Anticorps
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Reactivité
    • 244
    • 52
    • 47
    • 28
    • 23
    • 15
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 147
    • 140
    • 8
    • 4
    • 2
    Souris
    Clonalité
    • 158
    • 139
    • 2
    Monoclonal
    Conjugué
    • 139
    • 39
    • 30
    • 17
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp alpha Fetoprotein est non-conjugé
    Application
    • 152
    • 124
    • 87
    • 68
    • 53
    • 31
    • 28
    • 27
    • 27
    • 27
    • 16
    • 16
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    • 1
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    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificité
    The mouse monoclonal antibody AFP-01 reacts with human alpha-Fetoprotein (AFP), a 70 kDa oncofetal antigen. AFP is a major fetal plasma protein, but is not present in healthy adult tissues. Elevated AFP concentrations in adult plasma may be an early marker of hepatocellular carcinoma or teratoblastoma, while high concentrations in amniotic fluid may indicate severe congenital defects of a fetus.
    Réactivité croisée (Details)
    Other not tested, Human
    Purification
    Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    purified alpha-Fetoprotein
    Clone
    AFP-01
    Isotype
    IgG1
    Top Product
    Discover our top product AFP Anticorps primaire
  • Indications d'application
    ELISA: The antibody AFP-01 has been tested as the detection antibody in a sandwich ELISA for analysis of human alpha-fetoprotein in combination with antibody AFP-11 (cat. no. 11-384-C100).
    Western blotting: Recommended dilution: 1-2 μg/mL, non-reducing conditions.
    Immunoprecipitation: Interaction of the antibody AFP-01 with AFP is dependent on the presence of calcium ions (strongly inhibited by chelating agents). Such characteristics of the antibody can be exploited for immunoaffinity purification of APF under mild elution conditions.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Cermák, Símová, Pintzas, Horejsí, Andera: "Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules." dans: The Journal of biological chemistry, Vol. 277, Issue 10, pp. 7955-61, (2002) (PubMed).

  • Antigène
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Autre désignation
    alpha-Fetoprotein (AFP Produits)
    Synonymes
    anticorps FETA, anticorps HPAFP, anticorps alpha fetoprotein, anticorps alpha-fetoprotein, anticorps AFP, anticorps Afp
    Sujet
    Alpha fetoprotein,Alpha-fetoprotein (AFP) is present in fetal plasma, and it binds e.g. copper, nickel, and bilirubin. Measuring of alpha-fetoprotein level in amniotic fluid can reveal severe fetal defects. In adults, elevated AFP concentrations in the plasma can indicate hepatocellular carcinoma or teratoblastoma. In some individuals, hereditary persistance of alpha-fetoprotein can be observed without any obvious pathology.,AFP, FETA, HPAFP
    ID gène
    174
    UniProt
    P02771
    Pathways
    C21-Steroid Hormone Metabolic Process
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