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MME anticorps (Biotin)

MME Reactivité: Humain FACS, IP Hôte: Souris Monoclonal MEM-78 Biotin
N° du produit ABIN93931
  • Antigène Voir toutes MME Anticorps
    MME (Membrane Metallo-Endopeptidase (MME))
    Reactivité
    • 197
    • 44
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 106
    • 96
    • 2
    Souris
    Clonalité
    • 112
    • 91
    • 2
    Monoclonal
    Conjugué
    • 107
    • 19
    • 17
    • 13
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MME est conjugé à/à la Biotin
    Application
    • 111
    • 81
    • 79
    • 68
    • 37
    • 27
    • 20
    • 18
    • 10
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificité
    The antibody MEM-78 reacts with an extracellular epitope CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    Immunogène
    NALM-6 human pre-B cell line
    Clone
    MEM-78
    Isotype
    IgG1
    Top Product
    Discover our top product MME Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1 μg/mL.
    Commentaires

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." dans: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).

  • Antigène
    MME (Membrane Metallo-Endopeptidase (MME))
    Autre désignation
    CD10 (MME Produits)
    Synonymes
    anticorps CALLA, anticorps CD10, anticorps NEP, anticorps SFE, anticorps 6030454K05Rik, anticorps C85356, anticorps Nep, anticorps neprilysin, anticorps membrane metalloendopeptidase, anticorps membrane metallo endopeptidase, anticorps membrane metallo-endopeptidase, anticorps MME, anticorps Mme
    Classe de substances
    Chemical
    Sujet
    Membrane metalloendopeptidase,CD10 (neutral endopeptidase –, NEP, common acute lymphocytic leukemia antigen –, CALLA, membrane metallo-endopeptidase –, MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.,CALLA, Neprilysin, Neutral endopeptidase, Enkephalinase, Atriopeptidase, MME
    ID gène
    4311
    UniProt
    P08473
    Pathways
    Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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