CD2 anticorps
(2 références)-
- Antigène Voir toutes CD2 Anticorps
- CD2
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD2 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificité
- The antibody MEM-65 recognizes a unique extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells, also expressed by all thymocytes.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Human peripheral T cells.
- Clone
- MEM-65
- Isotype
- IgG1
- Top Product
- Discover our top product CD2 Anticorps primaire
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anti-CD2 (CD2) (AA 25-140) antibody
CD2 Reactivité: Souris FACS, WB, ELISA, IHC, ICC Hôte: Souris Monoclonal 3D1E3 unconjugated
anti-CD2 (CD2) (AA 25-140) antibodyCD2 Reactivité: Humain, Souris FACS, WB, ELISA, IHC, ICC Hôte: Souris Monoclonal 3D1B4 unconjugated
anti-CD2 (CD2) (N-Term) antibodyCD2 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-CD2 (CD2) antibody (FITC)CD2 Reactivité: Humain FACS Hôte: Souris Monoclonal LT2 FITC
anti-CD2 (CD2) antibody (PE)CD2 Reactivité: Humain FACS Hôte: Souris Monoclonal LT2 PE
anti-CD2 (CD2) (AA 1-351) antibodyCD2 Reactivité: Humain WB, IHC (p) Hôte: Souris Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 Reactivité: Humain FACS, IF, WB, Func Hôte: Souris Monoclonal 1E7E8-G4 unconjugated
anti-CD2 (CD2) antibodyCD2 Reactivité: Humain FACS, IP Hôte: Souris Monoclonal LT2 unconjugated
anti-CD2 (CD2) antibodyCD2 Reactivité: Humain FACS, Func Hôte: Souris Monoclonal TS1-8 unconjugated
anti-CD2 (CD2) (AA 25-209) antibodyCD2 Reactivité: Humain IF, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." dans: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
: "New monoclonal antibodies to human leucocyte surface molecule CD2." dans: Folia biologica, Vol. 43, Issue 6, pp. 245-6, (1998) (PubMed).
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: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." dans: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
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- Antigène
- CD2
- Autre désignation
- CD2 (CD2 Produits)
- Synonymes
- anticorps CD2, anticorps LFA-2, anticorps Ly-37, anticorps Ly37, anticorps SRBC, anticorps T11, anticorps CD2R, anticorps LFA2, anticorps OX-34, anticorps OX34, anticorps CD2 molecule, anticorps CD2 antigen, anticorps Cd2 molecule, anticorps CD2, anticorps Cd2
- Sujet
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
- ID gène
- 914
- UniProt
- P06729
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