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CD235ab anticorps (N-Term)

CD235a + CD235b Reactivité: Humain FACS, IHC (fro), IHC (p), AGG Hôte: Souris Monoclonal HIR2 unconjugated
N° du produit ABIN94041
  • Antigène Tous les produits CD235ab (CD235a + CD235b)
    CD235ab (CD235a + CD235b) (Glycophorin A + B (CD235a + CD235b))
    Épitope
    N-Term
    Reactivité
    Humain
    Hôte
    • 16
    • 1
    Souris
    Clonalité
    • 16
    • 1
    Monoclonal
    Conjugué
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD235ab est non-conjugé
    Application
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Aggregation (AGG)
    Specificité
    The mouse monoclonal antibody HIR2 recognizes an epitope within the N-terminal (extracellular) portion of CD235a (glycophorin A) and CD235b (glycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Synthetic peptide (Human, N-terminal)
    Clone
    HIR2
    Isotype
    IgG2b
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    CD235ab (CD235a + CD235b) (Glycophorin A + B (CD235a + CD235b))
    Autre désignation
    CD235ab (CD235a + CD235b Produits)
    Sujet
    CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A/B, GYPA/B, GPA/B, PAS-2/3, Sialoglycoprotein alpha/beta, GPSAT, GPErik, MSN blood group
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