CD27 anticorps
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- Antigène Voir toutes CD27 Anticorps
- CD27 (CD27 Molecule (CD27))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD27 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- The antibody LT27 reacts with an extracellular epitope of CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Human peripheral blood lymphocytes
- Clone
- LT27
- Isotype
- IgG2a
- Top Product
- Discover our top product CD27 Anticorps primaire
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anti-CD27 Molecule (CD27) (AA 1-260) antibody
CD27 Reactivité: Humain WB, ELISA, RNAi Hôte: Souris Monoclonal 1E2-A3 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 Reactivité: Humain FACS, ELISA, IHC, IF, StM, Coat Hôte: Souris Monoclonal LPFS2-1611 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 20-191) antibodyCD27 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 20-144) antibodyCD27 Reactivité: Humain FACS, ELISA Hôte: Souris Monoclonal 3B6D3 unconjugated
anti-CD27 Molecule (CD27) (AA 196-225) antibodyCD27 Reactivité: Humain FACS, WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 229-312) antibodyCD27 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 196-225), (C-Term) antibodyCD27 Reactivité: Humain FACS, WB Hôte: Lapin Polyclonal RB33726 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 Reactivité: Humain FACS, IHC, StM Hôte: Souris Monoclonal rLPFS2-1611 unconjugated Recombinant Antibody
anti-CD27 Molecule (CD27) antibodyCD27 Reactivité: Humain WB, IF Hôte: Lapin Monoclonal unconjugated
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- Indications d'application
- Flow cytometry: Recommended dilution: 2 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- CD27 (CD27 Molecule (CD27))
- Autre désignation
- CD27 (CD27 Produits)
- Sujet
- CD27 Molecule,CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.,T14, TNFRSF7, LPFS2, S152, Tp55
- ID gène
- 939
- UniProt
- P26842
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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