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Integrin Alpha2b anticorps (FITC)

Name: Integrin Alpha2b anticorps (FITC)
Brand: antibodies-online
SKU: ABIN94108
Price: 349.14 EUR
Availability: InStock

CD41 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-06 FITC

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD41 (MEM-06) FITC antibody (20 μL reagent / 100 μL of peripheral whole blood). (Integrin Alpha2b anticorps (FITC))

FACS

Surface staining of human platelets with anti-human CD41 (MEM-06) PE. (Integrin Alpha2b anticorps (FITC))

FACS

Separation of human CD41 positive thrombocytes (red-filled) from CD41 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD41 (MEM-06) FITC antibody (20 μL reagent / 100 μL of peripheral whole blood). (Integrin Alpha2b anticorps (FITC))

FACS

3 images

N° du produit ABIN94108

Fiche de données

Antigène Voir toutes Integrin Alpha2b (CD41) Anticorps

Integrin Alpha2b (CD41)
Reactivité
122

35

21

5

5

4

3

2

2

2

1

1

1

1

1
Humain
Hôte
78

46

26
Souris
Anticorps secondaires appropriés
Clonalité
100

44

1
Monoclonal
Conjugué
58

15

13

11

5

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp Integrin Alpha2b est conjugé à/à la FITC
Application
102

44

27

27

20

19

13

13

11

9

8

5

3

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Specificité

The antibody MEM-06 reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

Réactivité croisée (Details)

Human

Purification

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène

Leukocytes of patient suffering from LGL-type leukaemia.

Clone

MEM-06

Isotype

IgG1

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CD41 Reactivité: Souris FACS Hôte: Rat Monoclonal MWReg30 PE

Indications d'application

Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Commentaires

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

Restrictions

For Research Use only
Reconstitution

No reconstitution is necessary.

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Do not freeze.
Avoid prolonged exposure to light.

Stock

4 °C

Stockage commentaire

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Antigène

Integrin Alpha2b (CD41)

Autre désignation

CD41 (CD41 Produits)

Synonymes

anticorps AI172977, anticorps CD41, anticorps CD41B, anticorps GpIIb, anticorps alphaIIb, anticorps BDPLT16, anticorps BDPLT2, anticorps GP2B, anticorps GPIIb, anticorps GT, anticorps GTA, anticorps HPA3, anticorps integrin alpha 2b, anticorps integrin subunit alpha 2b, anticorps Itga2b, anticorps ITGA2B

Sujet

Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GTA

ID gène

3674

UniProt

P08514

Pathways

Integrin Complex