Integrin Alpha2b anticorps
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- Antigène Voir toutes Integrin Alpha2b (CD41) Anticorps
- Integrin Alpha2b (CD41)
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Reactivité
- Humain, Non-Human Primate
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Integrin Alpha2b est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
- Réactivité croisée (Details)
- Human, Non-Human Primates
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Clone
- HIP2
- Isotype
- IgG3
- Top Product
- Discover our top product CD41 Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." dans: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
: "
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[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." dans: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
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- Antigène
- Integrin Alpha2b (CD41)
- Autre désignation
- CD41b (CD41 Produits)
- Sujet
- Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,GT, GTA, GP2B, HPA3, GPIIb
- ID gène
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
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