CD9 anticorps

N° du produit ABIN94242

Détail du produit anti-CD9 anticorps

Antigène: CD9

Reactivité: Humain, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD9 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Specificité: The antibody IVA50 reacts with an extracellular epitope of CD9 antigen (bovine), a 24 kDa single transmembrane polypeptide expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes. This antibody crossreacts with CD9 on human platelets.

Réactivité croisée (Details): Human, Bovine

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Bovine thrombocytes.

Clone: IVA50

Isotype: IgG2

Information d'application

Indications d'application: Western blotting: Recommended dilution: 1 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-CD9 (ABIN94242)

de Pontes, Altei, Galan, Bilić, Guillemin, Kuleš, Horvatić, Ribeiro, de Paula, Pereira, Lucheis, Mrljak, Eckersall, Ferreira, Dos Santos: "Extracellular vesicles in infectious diseases caused by protozoan parasites in buffaloes." dans: The journal of venomous animals and toxins including tropical diseases, Vol. 26, pp. e20190067, (2020) (PubMed).

Tomásková, Dusinský, Horovská, Simon: "A set of monoclonal antibodies specific for bovine cell surface molecule CD9." dans: Folia biologica, Vol. 45, Issue 5, pp. 225-6, (2000) (PubMed).

Mateo, Perez de la Lastra, Moreno, Dusinsky, Bilka, Simon, Horovska, Llanes: "Biochemical characterization of antigens detected with anti-platelet monoclonal antibodies." dans: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 363-70, (1997) (PubMed).

Naessens, Howard, Hopkins: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." dans: Immunology today, Vol. 18, Issue 8, pp. 365-8, (1997) (PubMed).

Sopp, Howard: "Investigation of PC36 (BoCD45R)." dans: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 271-4, (1997) (PubMed).

Détails sur CD9

Antigène: CD9

Autre désignation: CD9 (CD9 Produits)

Sujet: CD9 Molecule,CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.,MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29

ID gène: 280746

UniProt: P30932

Pathways: Response to Water Deprivation, Cell-Cell Junction Organization