CD9 anticorps
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- Antigène Voir toutes CD9 Anticorps
- CD9
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD9 est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Cytometry by Time of Flight (CyTOF)
- Specificité
- The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Pre-B cell line NALM-6.
- Clone
- MEM-61
- Isotype
- IgG1
- Top Product
- Discover our top product CD9 Anticorps primaire
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- Indications d'application
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Flow cytometry: Recommended dilution: 1-4 μg/mL.
Western blotting: Recommended dilution: 2-4 μg/mL, non-reducing conditions.
Immunohistochemistry (paraffin sections): Recommended dilution: 20 μg/mL, positive tissue: prostate. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent pericellular proteolysis." dans: Molecular biology of the cell, Vol. 20, Issue 7, pp. 2030-40, (2009) (PubMed).
: "Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance." dans: American journal of physiology. Cell physiology, Vol. 293, Issue 5, pp. C1660-8, (2007) (PubMed).
: "Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 5, pp. 2724-33, (2001) (PubMed).
: "
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Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent pericellular proteolysis." dans: Molecular biology of the cell, Vol. 20, Issue 7, pp. 2030-40, (2009) (PubMed).
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- Antigène
- CD9
- Autre désignation
- CD9 (CD9 Produits)
- Synonymes
- anticorps BTCC-1, anticorps DRAP-27, anticorps MIC3, anticorps MRP-1, anticorps TSPAN-29, anticorps TSPAN29, anticorps Tspan29, anticorps cd9, anticorps wu:fb61g04, anticorps zgc:73383, anticorps zgc:85743, anticorps CD9 molecule, anticorps CD9 antigen, anticorps CD9 molecule a, anticorps CD9, anticorps Cd9, anticorps cd9a
- Sujet
- CD9 Molecule,CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.,MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, BA2
- ID gène
- 928
- UniProt
- P21926
- Pathways
- Response to Water Deprivation, Cell-Cell Junction Organization
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