CD9 anticorps (FITC)

N° du produit ABIN94247

Détail du produit anti-CD9 anticorps (FITC)

Antigène: CD9

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD9 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Pre-B cell line NALM-6.

Clone: MEM-61

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Commentaires:

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Stockage

Reconstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-CD9 (FITC) (ABIN94247)

Lafleur, Xu, Hemler: "Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent pericellular proteolysis." dans: Molecular biology of the cell, Vol. 20, Issue 7, pp. 2030-40, (2009) (PubMed).

Singh, Sugimoto, Dhawan, Harris: "Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance." dans: American journal of physiology. Cell physiology, Vol. 293, Issue 5, pp. C1660-8, (2007) (PubMed).

Stöckl, Majdic, Fischer, Maurer, Knapp: "Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 5, pp. 2724-33, (2001) (PubMed).

Détails sur CD9

Antigène: CD9

Autre désignation: CD9 (CD9 Produits)

Synonymes: anticorps BTCC-1, anticorps DRAP-27, anticorps MIC3, anticorps MRP-1, anticorps TSPAN-29, anticorps TSPAN29, anticorps Tspan29, anticorps cd9, anticorps wu:fb61g04, anticorps zgc:73383, anticorps zgc:85743, anticorps CD9 molecule, anticorps CD9 antigen, anticorps CD9 molecule a, anticorps CD9, anticorps Cd9, anticorps cd9a

Sujet: CD9 Molecule,CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.,MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, BA2

ID gène: 928

UniProt: P21926

Pathways: Response to Water Deprivation, Cell-Cell Junction Organization