CD97 anticorps
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- Antigène Voir toutes CD97 Anticorps
- CD97
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD97 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificité
- The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- PHA-activated peripheral blood cells
- Clone
- MEM-180
- Isotype
- IgG1
- Top Product
- Discover our top product CD97 Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 5 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding." dans: International journal of cancer. Journal international du cancer, Vol. 112, Issue 5, pp. 815-22, (2004) (PubMed).
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N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding." dans: International journal of cancer. Journal international du cancer, Vol. 112, Issue 5, pp. 815-22, (2004) (PubMed).
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- Antigène
- CD97
- Autre désignation
- CD97 (CD97 Produits)
- Synonymes
- anticorps AA409984, anticorps TM7LN1, anticorps adhesion G protein-coupled receptor E5, anticorps Adgre5, anticorps ADGRE5
- Sujet
- Adhesion G protein-coupled receptor E5,CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.,TM7LN1, ADGRE5
- ID gène
- 976
- UniProt
- P48960
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