The antibody MEM-131 reacts with CD99R, an extracellular epitope restricted to a subset of CD99 Molecule expressed on myeloid cells, NK cells and T lymphocytes.
Réactivité croisée (Details)
Human
Purification
Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
Pureté
> 95 % (by SDS-PAGE)
Immunogène
HPB-ALL human peripheral blood leukemia T-cell line
CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells.,MIC2, HBA71, blood group Xg