SOCS3 anticorps

N° du produit ABIN94467

Détail du produit anti-SOCS3 anticorps

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOCS3 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody SO1 reacts with SOCS3, an intracellular cytokine signaling inhibitor.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Full-length SOCS3 protein.

Clone: SO1

Isotype: IgG2b

Information d'application

Indications d'application: Western blotting: Positive control: HeLa human cervix carcinoma cell line, reducing conditions.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-SOCS3 (ABIN94467)

Neuwirt, Puhr, Cavarretta, Mitterberger, Hobisch, Culig: "Suppressor of cytokine signalling-3 is up-regulated by androgen in prostate cancer cell lines and inhibits androgen-mediated proliferation and secretion." dans: Endocrine-related cancer, Vol. 14, Issue 4, pp. 1007-19, (2007) (PubMed).

Détails sur SOCS3

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Autre désignation: SOCS3 (SOCS3 Produits)

Synonymes: anticorps socs3, anticorps fj09e12, anticorps zgc:56537, anticorps wu:fj09e12, anticorps MGC64393, anticorps MGC75749, anticorps xsocs3, anticorps MGC81248, anticorps atod4, anticorps cis3, anticorps cish3, anticorps socs-3, anticorps ssi-3, anticorps ssi3, anticorps SOCS3, anticorps ATOD4, anticorps CIS3, anticorps Cish3, anticorps SOCS-3, anticorps SSI-3, anticorps SSI3, anticorps Cis3, anticorps EF-10, anticorps Ef10, anticorps Ssi3, anticorps Socs-3, anticorps Ssi-3, anticorps suppressor of cytokine signaling 3a, anticorps suppressor of cytokine signaling 3 S homeolog, anticorps suppressor of cytokine signaling 3, anticorps suppressor of cytokine signaling 3 L homeolog, anticorps socs3a, anticorps socs3.S, anticorps socs3, anticorps socs3.L, anticorps SOCS3, anticorps Socs3

Sujet: Suppressor of cytokine signaling 3,SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.,SOCS-3, CIS3, SSI3

ID gène: 9021

UniProt: Q6FI39

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus, Hepatitis C