Kinesin anticorps (AA 331-906)

N° du produit ABIN94498

Détail du produit anti-Kinesin anticorps

Antigène: Kinesin

Épitope: AA 331-906

Reactivité: Humain, Souris, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kinesin est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Specificité: The polyclonal antibody detects total level of endogenous kinesin protein (intracellular antigen).

Réactivité croisée (Details): Human, Mouse, Porcine, Other not tested

Purification: Purified by ligand affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: stalk domain of human kinesin (aa 331-906) expressed in E. coli (FKHC3)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-Kinesin (ABIN94498)

Malcová-Janatová, Richterová, Dráber, Hasek: "Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains." dans: Folia microbiologica, Vol. 49, Issue 6, pp. 665-70, (2005) (PubMed).

Détails sur Kinesin

Antigène: Kinesin

Abstract: Kinesin Produits

Synonymes: anticorps kinesin, anticorps putative kinesin, anticorps Tc00.1047053510323.120, anticorps Tc00.1047053508153.200, anticorps LmjF29.2390, anticorps LINJ_29_2500, anticorps LBRM_29_2360

Sujet: Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.,KIN