Ensa anticorps (Middle Region)

N° du produit ABIN950376

Détail du produit anti-Ensa anticorps

Antigène: Ensa (ENSA) (Endosulfine alpha (ENSA))

Épitope: AA 46-74, Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ensa est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human and Mouse Alpha-endosulfine (ENSA) (Center).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 46-74 amino acids from the Central region of Human ENSA.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Ensa

Antigène: Ensa (ENSA) (Endosulfine alpha (ENSA))

Autre désignation: alpha-Endosulfine (ENSA) (ENSA Produits)

Synonymes: anticorps ARPP-19e, anticorps 1700020C18Rik, anticorps 2610007F17Rik, anticorps AI451924, anticorps ensa, anticorps si:dkeyp-24a7.3, anticorps ensaa, anticorps endosulfine alpha, anticorps endosulfine alpha a, anticorps endosulfine alpha S homeolog, anticorps ENSA, anticorps Ensa, anticorps ensa, anticorps ensaa, anticorps ensa.S

Sujet: ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes.Synonyms: ARPP-19e

Poids moléculaire: 13389 Da

ID gène: 2029

NCBI Accession: NP_004427