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beta Arrestin 1 anticorps (C-Term)

ARRB1 Reactivité: Humain WB, IF, IHC (p), FACS, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN950521
  • Antigène Voir toutes beta Arrestin 1 (ARRB1) Anticorps
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    Épitope
    • 19
    • 11
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 343-371, C-Term
    Reactivité
    • 74
    • 47
    • 33
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 78
    • 11
    • 1
    Lapin
    Clonalité
    • 72
    • 18
    Polyclonal
    Conjugué
    • 53
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp beta Arrestin 1 est non-conjugé
    Application
    • 68
    • 35
    • 33
    • 26
    • 16
    • 14
    • 13
    • 11
    • 8
    • 8
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to Arrestin beta-1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogène
    KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human ARRB1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ARRB1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) sodium azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    Autre désignation
    Arrestin beta-1 / ARRB1 (ARRB1 Produits)
    Synonymes
    anticorps arrb1, anticorps MGC83787, anticorps arb1, anticorps arr1, anticorps barr1, anticorps betaarr1, anticorps 1200006I17Rik, anticorps AW208571, anticorps G430100A01Rik, anticorps ARB1, anticorps ARR1, anticorps BARRES, anticorps arrestin beta 1, anticorps arrestin, beta 1, anticorps arrestin beta 1 L homeolog, anticorps beta-arrestin 1, anticorps putative beta-arrestin 1, anticorps ARRB1, anticorps arrb1, anticorps arrb1.L, anticorps CpipJ_CPIJ016988, anticorps CpipJ_CPIJ017114, anticorps Smp_122900, anticorps Smp_126080, anticorps Smp_176980, anticorps Smp_152290, anticorps Arrb1
    Sujet
    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.Synonyms: ARR1, Beta-arrestin-1
    ID gène
    408
    NCBI Accession
    NP_004032
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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