CRYBA1 anticorps (Middle Region)

N° du produit ABIN950651

Détail du produit anti-CRYBA1 anticorps

Antigène: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Épitope: AA 111-141, Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYBA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human and Mouse Beta-crystallin A3.

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 111-141 amino acids from the Central region of Human CRYBA1. Genename: CRYBA1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CRYBA1

Antigène: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Autre désignation: beta-Crystallin A3 (CRYBA1 Produits)

Synonymes: anticorps CRYB1, anticorps CTRCT10, anticorps BA3/A1, anticorps Cryb, anticorps BA3A1C, anticorps beta-A3, anticorps cryba1, anticorps zgc:92688, anticorps CRYBA3, anticorps cryb1, anticorps zgc:92720, anticorps crystallin beta A1, anticorps crystallin, beta A1, anticorps crystallin, beta A1a, anticorps crystallin beta A1 L homeolog, anticorps crystallin, beta A1b, anticorps CRYBA1, anticorps Cryba1, anticorps cryba1a, anticorps cryba1.L, anticorps cryba1, anticorps cryba1b

Sujet: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'Synonyms: CRYB1, CRYBA1

Poids moléculaire: 25150 Da

ID gène: 1411

NCBI Accession: NP_005199