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CD130/gp130 anticorps (C-Term)
IL6ST
Reactivité: Humain
WB, IHC (p), EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-CD130/gp130 anticorps
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Antigène
Voir toutes CD130/gp130 (IL6ST) Anticorps
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Épitope
Tous les épitopes à travers CD130/gp130 Anticorps.
AA 878-906, C-Term
Reactivité
Toutes les réactivités sur CD130/gp130 Anticorps
Humain
Hôte
Toutes les hôtes sur CD130/gp130 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CD130/gp130 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CD130/gp130 Anticorps
Cet anticorp CD130/gp130 est non-conjugé
Application
Tous les applications à travers CD130/gp130 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificité
This antibody reacts to CD130.
Réactivité croisée (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogène
KLH conjugated synthetic peptide between 878-906 amino acids from the C-terminal region of human CD130
Isotype
Ig Fraction
Top Product
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur CD130/gp130
(cache)
Antigène
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Autre désignation
CD130 / IL6ST (IL6ST Produits )
Synonymes
anticorps CD130, anticorps CDW130, anticorps GP130, anticorps IL-6RB, anticorps 5133400A03Rik, anticorps AA389424, anticorps BB405851, anticorps D13Ertd699e, anticorps gp130, anticorps Ac1055, anticorps Gp130, anticorps Il-6rb, anticorps IL-6, anticorps interleukin 6 signal transducer, anticorps IL6ST, anticorps Il6st, anticorps il6st
Sujet
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
Poids moléculaire
103537 Da
ID gène
3572
NCBI Accession
NP_002175
Pathways
Signalistation JAK/STAT , Cellular Glucan Metabolic Process , Autophagy , Smooth Muscle Cell Migration , Cancer Immune Checkpoints
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