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CTLA4 anticorps (FITC)
CTLA4
Reactivité: Humain
FACS
Hôte: Souris
Monoclonal
A3-4H2-H12
FITC
Détail du produit anti-CTLA4 anticorps (FITC)
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Antigène
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CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Reactivité
Toutes les réactivités sur CTLA4 Anticorps
Humain
Hôte
Toutes les hôtes sur CTLA4 Anticorps
Souris
Clonalité
Toutes les clonalités sur CTLA4 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CTLA4 Anticorps
Cet anticorp CTLA4 est conjugé à/à la FITC
Application
Tous les applications à travers CTLA4 Anticorps.
Flow Cytometry (FACS)
Specificité
Recognizes Human CTLA-4 (CD152).
Purification
Affinity Chromatography on Protein G
Immunogène
Activated T cells Donor: Balb/c mouse Fusion Partner: SP 2/0 myeloma
Clone
A3-4H2-H12
Isotype
IgG2a
Top Product
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.1 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur CTLA4
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Antigène
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Autre désignation
CD152 / CTLA4 (CTLA4 Produits )
Synonymes
anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4
Sujet
Human CTLA-4 (also known as Cytotoxic T lymphocyte-associated antigen-4, CD152) is a structural homologue of T cell co-stimulatory receptor CD28. CTLA-4 binds to the same ligands (CD80 and CD86) as CD28 but with much higher avidity. It is expressed at very low levels on the cell surface of activated T cells, and is found primarily in the post-Golgi or endosomal compartments of the cell. There is a high degree of overall homology between human and mouse CTLA-4 (>70 % ), and the cytoplasmic domains of the human, mouse and rabbit sequences are completely conserved. CD152 antibodies have shown both stimulatory and negative regulatory roles in functional experiments.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
ID gène
1493
NCBI Accession
NP_001032720
UniProt
P16410
Pathways
Cancer Immune Checkpoints
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