BST1 anticorps

N° du produit ABIN951197

Détail du produit anti-BST1 anticorps

Antigène: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp BST1 est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: This Monoclonal Antibody reacts with Mouse CD157.

Purification: Protein G Chromatography

Immunogène: T cell hybridoma J774. Donor: Balb/c mouse spleen cells. Fusion Partner: NSO Mouse Myelom a Partner.

Clone: KT157

Isotype: IgG2c

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BST1

Antigène: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Autre désignation: CD157 / BST1 (BST1 Produits)

Synonymes: anticorps BST1, anticorps 114/A10, anticorps A530073F09, anticorps BP-3, anticorps Bp3, anticorps Bsta1, anticorps CD157, anticorps Ly65, anticorps bone marrow stromal cell antigen 1, anticorps BST1, anticorps Bst1

Sujet: CD157 also known as BP-3 Alloantigen or Bone marrow Stromal cell antigen-1 (BST-1), is a 38-48 KDa differentially glycosylated glycosylphosphatidylinositol (GPI) anchored cell surface glycoprotein. CD157, like CD38 belongs to a family of genetically related pleiotropic ectoenzymes. The CD157 antigen is expressed on thymocytes, bone marrow B cells, neutrophils, macrophages, stromal cells, intestinal epithelial cells, the collecting tubules of the kidney and reticular cells in lymph nodes. The CD157 receptor has ADP ribosyl cyclase and cyclic ADP ribose hydrolase biochemical activities. Studies show CD157 is a receptor that induces reorganization of the cytoskeleton and significant changes in cell shape. CD157 is also a mediator of neutrophil adhesion and migration. Signals mediated by CD157 act through modulation of cytosolic [Ca2+]. CD157 is also involved in cellular adhesion to the extracellular matrix.Synonyms: ADP-ribosyl cyclase 2, BST-1, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2

ID gène: 12182

NCBI Accession: NP_033893

UniProt: Q64277