IGSF8 anticorps (Middle Region)

N° du produit ABIN951296

Détail du produit anti-IGSF8 anticorps

Antigène: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Épitope: AA 233-262, Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGSF8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects IGSF8 (Center).

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogène: Synthetic peptide (233-262 aa) - KLH conjugated - corresponding to internal domain of human IGSF8.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IGSF8

Antigène: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Autre désignation: CD316 / IGSF8 (IGSF8 Produits)

Synonymes: anticorps MGC77222, anticorps IGSF8, anticorps MGC151661, anticorps CD316, anticorps CD81P3, anticorps EWI-2, anticorps EWI2, anticorps KCT-4, anticorps LIR-D1, anticorps PGRL, anticorps AA033172, anticorps AU041109, anticorps ESTM34, anticorps R75384, anticorps immunoglobulin superfamily, member 8, anticorps immunoglobulin superfamily member 8, anticorps igsf8, anticorps IGSF8, anticorps Igsf8

Sujet: GSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.Synonyms: CD81 partner 3, CD81P3, EWI2, Glu-Trp-Ile EWI motif-containing protein 2, Immunoglobulin superfamily member 8, KCT4, Keratinocytes-associated transmembrane protein 4, LIR-D1

ID gène: 93185

NCBI Accession: NP_001193594