CLASP2 anticorps (AA 1005-1034)

N° du produit ABIN951541

Détail du produit anti-CLASP2 anticorps

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Épitope: AA 1005-1034

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLASP2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 1005~1034 amino acids from the Y1019 region of human CLASP2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CLASP2

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Autre désignation: CLASP2 (CLASP2 Produits)

Synonymes: anticorps zgc:77279, anticorps DKFZp459M112, anticorps 1500004F14Rik, anticorps 8030404L10Rik, anticorps C77448, anticorps CLASP2beta, anticorps mKIAA0627, anticorps cytoplasmic linker associated protein 2, anticorps CLIP associating protein 2, anticorps clasp2, anticorps CLASP2, anticorps Clasp2

Sujet: CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.Synonyms: CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, KIAA0627, Protein Orbit homolog 2, hOrbit2

Poids moléculaire: 141133 Da

ID gène: 9606

Pathways: Dynamique des Microtubules, Maintenance of Protein Location