Complement Factor H anticorps (Middle Region)

N° du produit ABIN951646

Détail du produit anti-Complement Factor H anticorps

Antigène: Complement Factor H (CFH)

Épitope: AA 751-780, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement Factor H est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CFH.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Complement Factor H

Antigène: Complement Factor H (CFH)

Abstract: CFH Produits

Synonymes: anticorps AHUS1, anticorps AMBP1, anticorps ARMD4, anticorps ARMS1, anticorps CFHL3, anticorps FH, anticorps FHL1, anticorps HF, anticorps HF1, anticorps HF2, anticorps HUS, anticorps Mud-1, anticorps NOM, anticorps Sas-1, anticorps Sas1, anticorps Fh, anticorps CFH, anticorps im:7147412, anticorps si:ch211-207o17.2, anticorps fH, anticorps armd4, anticorps arms1, anticorps cfh, anticorps cfhl3, anticorps fhl1, anticorps hf1, anticorps hf2, anticorps hus, anticorps complement factor H, anticorps complement component factor h, anticorps complement factor H-related protein 5, anticorps complement factor H L homeolog, anticorps CFH, anticorps Cfh, anticorps cfh, anticorps LOC100399888, anticorps LOC100733902, anticorps cfh.L

Sujet: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2

Poids moléculaire: 139096 Da

ID gène: 3075

NCBI Accession: NP_000177

Pathways: Système du Complément, Cellular Response to Molecule of Bacterial Origin