anticorps CTDSP1, anticorps NIF3, anticorps NLI-IF, anticorps NLIIF, anticorps SCP1, anticorps fj83f12, anticorps im:7141428, anticorps wu:fj83f12, anticorps zgc:113169, anticorps GIP, anticorps Nif3, anticorps CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, anticorps CTD small phosphatase 1, anticorps carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, anticorps CTDSP1, anticorps Ctdsp1, anticorps ctdsp1, anticorps HCAG_04820, anticorps CTRG_06220
Sujet
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cellsSynonyms: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, NIF3, NLI-IF, NLI-interacting factor 3, NLIIF, SCP1, Small C-terminal domain phosphatase 1