ERI1 anticorps (N-Term)
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- Antigène Voir toutes ERI1 Anticorps
- ERI1 (Exoribonuclease 1 (ERI1))
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Épitope
- AA 79-109, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ERI1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes Human ERI1 / THEX1 (N-term).
- Purification
- Affinity Chromatography on Protein A
- Immunogène
- KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of Human ERI1
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ERI1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ERI1 (Exoribonuclease 1 (ERI1))
- Autre désignation
- ERI1 / THEX1 (ERI1 Produits)
- Synonymes
- anticorps THEX1, anticorps thex1, anticorps zgc:110635, anticorps hexo, anticorps Eri-1, anticorps 3'HEXO, anticorps HEXO, anticorps 3'hexo, anticorps 3110010F15Rik, anticorps Thex1, anticorps eri-1, anticorps RGD1308378, anticorps exoribonuclease 1, anticorps three prime repair exonuclease 1, anticorps exoribonuclease 1 L homeolog, anticorps 3'-5' exonuclease eri-1, anticorps ERI1, anticorps CpipJ_CPIJ003945, anticorps eri1, anticorps eri1.L, anticorps Eri1, anticorps eri-1
- Sujet
- RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.Synonyms: 3'-5' exonuclease ERI1, 3'-5' exoribonuclease 1, 3'EXO, Eri-1 homolog, HEXO, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo
- Poids moléculaire
- 40064 Da
- ID gène
- 90459
- NCBI Accession
- NP_699163
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