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GCLC anticorps (N-Term)

GCLC Reactivité: Humain WB, IF, IHC (p), FACS, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN952477
  • Antigène Voir toutes GCLC Anticorps
    GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
    Épitope
    • 9
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-34, N-Term
    Reactivité
    • 59
    • 22
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 4
    Lapin
    Clonalité
    • 50
    • 13
    Polyclonal
    Conjugué
    • 37
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp GCLC est non-conjugé
    Application
    • 45
    • 26
    • 22
    • 12
    • 10
    • 9
    • 9
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes Human GCL / GLCLC (N-term).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogène
    KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of Human GCLC / GLCLC
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GCLC Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
    Autre désignation
    GCLC / GLCLC (GCLC Produits)
    Sujet
    Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.Synonyms: GCS heavy chain, GLCL, GLCLC, Gamma-ECS, Gamma-glutamylcysteine synthetase, Glutamate-cysteine ligase catalytic subunit
    Poids moléculaire
    72766 Da
    ID gène
    2729
    NCBI Accession
    NP_001184044
    Pathways
    Cell RedoxHomeostasis
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