GNAS anticorps (C-Term)
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- Antigène Voir toutes GNAS Anticorps
- GNAS (GNAS Complex Locus (GNAS))
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Épitope
- AA 286-315, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GNAS est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogène
- KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of Human GNAS
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GNAS Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- GNAS (GNAS Complex Locus (GNAS))
- Autre désignation
- GNAS (GNAS Produits)
- Synonymes
- anticorps AHO, anticorps C20orf45, anticorps GNAS1, anticorps GPSA, anticorps GSA, anticorps GSP, anticorps NESP, anticorps PHP1A, anticorps PHP1B, anticorps PHP1C, anticorps POH, anticorps GNAS, anticorps PORGSA1, anticorps G-alpha-S, anticorps 5530400H20Rik, anticorps A930027G11Rik, anticorps C130027O20Rik, anticorps Galphas, anticorps Gnas1, anticorps Gnasxl, anticorps Gsa, anticorps Nesp, anticorps Nespl, anticorps Oed-Sml, anticorps Oedsml, anticorps P1, anticorps P2, anticorps P3, anticorps G-alpha-s, anticorps gnas-a, anticorps Gnpas, anticorps Nesp55, anticorps gnal, anticorps Gnas, anticorps GNAS complex locus, anticorps guanine nucleotide-binding protein G(s) subunit alpha, anticorps GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, anticorps GNAS complex locus S homeolog, anticorps neuroendocrine secretory protein 55-like, anticorps GNAS, anticorps LOC694289, anticorps LOC469986, anticorps Gnas, anticorps gnas.S, anticorps gnas, anticorps LOC100346323, anticorps LOC100442753, anticorps LOC100732436
- Sujet
- Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
- Poids moléculaire
- 44,250 Da
- ID gène
- 9606
- Pathways
- Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
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