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GSTa2 anticorps (N-Term)

GSTa2 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN952640
  • Antigène Voir toutes GSTa2 Anticorps
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Épitope
    • 14
    • 8
    • 7
    • 2
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 38
    • 3
    • 1
    Humain
    Hôte
    • 35
    • 4
    Lapin
    Clonalité
    • 37
    • 2
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GSTa2 est non-conjugé
    Application
    • 32
    • 24
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes Human GSTA2 / GST2 (N-term).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogène
    KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human GSTA2 / GST2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GSTa2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Autre désignation
    GSTA2 / GST2 (GSTa2 Produits)
    Synonymes
    anticorps GSTA1, anticorps GST2, anticorps GSTA2-2, anticorps GTA2, anticorps GTH2, anticorps Gsta1, anticorps Gst2-2, anticorps Gstc-2, anticorps Gstc2, anticorps glutathione S-transferase alpha 2, anticorps glutathione S-transferase, anticorps glutathione S-transferase, alpha 2 (Yc2), anticorps GSTA2, anticorps Gsta2
    Sujet
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.Synonyms: GST class-alpha member 2, GST-gamma, GSTA2-2, GTH2, Glutathione S-transferase A2, HA subunit 2
    ID gène
    2939
    NCBI Accession
    NP_000837
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