anticorps HMG-R, anticorps HMGA1A, anticorps HMGIY, anticorps Hmgi, anticorps Hmgiy, anticorps hmga1, anticorps hmgiy, anticorps wu:fb12b06, anticorps wu:fb18f11, anticorps wu:fc19f01, anticorps wu:fi38b05, anticorps zgc:85677, anticorps AL023995, anticorps Hmga1a, anticorps Hmga1b, anticorps Hmgy, anticorps HMG-I(Y), anticorps HMG-Y, anticorps HMGA1, anticorps zgc:153948, anticorps high mobility group AT-hook 1, anticorps high mobility group protein HMG-I/HMG-Y, anticorps high mobility group AT-hook 1a, anticorps high mobility group AT-hook 1b, anticorps HMGA1, anticorps Hmga1, anticorps TSC_c24220, anticorps hmga1a, anticorps LOC705105, anticorps hmga1b
Sujet
HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.Synonyms: High mobility group AT-hook protein 1, High mobility group protein A1, High mobility group protein HMG-I/HMG-Y, High mobility group protein R