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IL12RB2 anticorps (C-Term)
IL12RB2
Reactivité: Humain
WB, FACS, IHC (p), EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-IL12RB2 anticorps
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Antigène
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IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Épitope
Tous les épitopes à travers IL12RB2 Anticorps.
AA 759-788, C-Term
Reactivité
Toutes les réactivités sur IL12RB2 Anticorps
Humain
Hôte
Toutes les hôtes sur IL12RB2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur IL12RB2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers IL12RB2 Anticorps
Cet anticorp IL12RB2 est non-conjugé
Application
Tous les applications à travers IL12RB2 Anticorps.
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificité
This antibody detects human IL12RB2 at C-term.
Réactivité croisée (Details)
Species reactivity (tested):Human
Purification
Purified through a protein A column; followed by peptide affinity purification.
Immunogène
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 759-788aa) of human IL12RB2.
Isotype
Ig Fraction
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur IL12RB2
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Antigène
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Autre désignation
IL12RB2 (IL12RB2 Produits )
Synonymes
anticorps IL12RB2, anticorps A930027I18Rik, anticorps IL-12RB2, anticorps Ifnm, anticorps interleukin 12 receptor subunit beta 2, anticorps interleukin 12 receptor, beta 2, anticorps IL12RB2, anticorps Il12rb2
Sujet
The protein encoded by the IL12RB2 gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Synonyms: IL-12 receptor beta-2, IL-12R-beta-2, Interleukin-12 receptor beta-2 chain
ID gène
3595
NCBI Accession
NP_001550
Pathways
Signalistation JAK/STAT
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