MUTYH anticorps (Middle Region)

N° du produit ABIN953552

Détail du produit anti-MUTYH anticorps

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Épitope: AA 352-381, Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUTYH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes MUTYH.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the central region (between 352-381aa) of human MUTYH.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MUTYH

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Autre désignation: MUTYH (MUTYH Produits)

Sujet: MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair and initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog

ID gène: 4595

NCBI Accession: NP_001041636

Pathways: Réparation de l'ADN