Neurofibromin 1 anticorps (Internal Region)

N° du produit ABIN953662

Détail du produit anti-Neurofibromin 1 anticorps

Antigène: Neurofibromin 1 (NF1)

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurofibromin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of total NF1 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide from Human NF1. Epitope: Internal.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: Neurofibromin (NF1 Produits)

Synonymes: anticorps NFNS, anticorps VRNF, anticorps WSS, anticorps CG8318, anticorps Dmel\\CG8318, anticorps NF-1, anticorps NF1, anticorps Nf-1, anticorps dNF1, anticorps nf1, anticorps fe06d03, anticorps hm:zehn0874, anticorps wu:fe06d03, anticorps zehn0874, anticorps AW494271, anticorps E030030H24Rik, anticorps neurofibromin 1, anticorps Neurofibromin 1, anticorps neurofibromin 1a, anticorps neurofibromin, anticorps putative neurofibromin, anticorps NF1, anticorps Nf1, anticorps nf1a, anticorps LOC593418, anticorps LOC5570549, anticorps CpipJ_CPIJ011774, anticorps Smp_148460

Sujet: Mutations linked to neurofibromatosis type 1 led to the identification of NF1. NF1 encodes the protein neurofibromin, which appears to be a negative regulator of the ras signal transduction pathway. In addition to type 1 neurofibromatosis, mutations in NF1 can also lead to juvenile myelomonocytic leukemia. Alternatively spliced NF1 mRNA transcripts have been isolated, although their functions, if any, remain unclear.Synonyms: NF-1, NF1

ID gène: 4763

NCBI Accession: NP_000258

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity