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Neurofibromin 1 anticorps (Internal Region)

NF1 Reactivité: Humain, Souris, Rat WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN953662
  • Antigène Voir toutes Neurofibromin 1 (NF1) Anticorps
    Neurofibromin 1 (NF1)
    Épitope
    • 15
    • 15
    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 61
    • 48
    • 32
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 71
    • 6
    Lapin
    Clonalité
    • 71
    • 6
    Polyclonal
    Conjugué
    • 25
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Neurofibromin 1 est non-conjugé
    Application
    • 39
    • 39
    • 26
    • 17
    • 13
    • 10
    • 9
    • 7
    • 7
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects endogenous levels of total NF1 protein.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography
    Immunogène
    Synthetic peptide from Human NF1. Epitope: Internal.
    Isotype
    IgG
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Neurofibromin 1 (NF1)
    Autre désignation
    Neurofibromin (NF1 Produits)
    Sujet
    Mutations linked to neurofibromatosis type 1 led to the identification of NF1. NF1 encodes the protein neurofibromin, which appears to be a negative regulator of the ras signal transduction pathway. In addition to type 1 neurofibromatosis, mutations in NF1 can also lead to juvenile myelomonocytic leukemia. Alternatively spliced NF1 mRNA transcripts have been isolated, although their functions, if any, remain unclear.Synonyms: NF-1, NF1
    ID gène
    4763
    NCBI Accession
    NP_000258
    Pathways
    cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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