This antibody is expected to recognise isoform 2 (NP_004545.2), Isoform 3 (NP_001185894.1), Isofrom 4 (NP_001185895.1) and Isofrom 5 (NP_001185896.1).
Réactivité croisée (Details)
Species reactivity (expected):Mouse, Rat, Dog, Pig. Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Immunogène
Peptide with sequence from the C Terminus of the protein sequence according to NP_004545.2, NP_001185894.1, NP_001185895.1, NP_001185896.1. Genename: NFATC4
The protein is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a pre-existing cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4.Synonyms: NF-ATc4, Nuclear factor of activated T-cells, cytoplasmic 4