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PABPN1 anticorps (C-Term)
PABPN1
Reactivité: Humain
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-PABPN1 anticorps
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Antigène
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PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Épitope
Tous les épitopes à travers PABPN1 Anticorps.
AA 269-298, C-Term
Reactivité
Toutes les réactivités sur PABPN1 Anticorps
Humain
Hôte
Toutes les hôtes sur PABPN1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur PABPN1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PABPN1 Anticorps
Cet anticorp PABPN1 est non-conjugé
Application
Tous les applications à travers PABPN1 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody recognizes Human PABPN1 (C-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogène
KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human PABPN1
Isotype
Ig Fraction
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur PABPN1
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Antigène
PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Autre désignation
PABPN1 (PABPN1 Produits )
Synonymes
anticorps OPMD, anticorps PAB2, anticorps PABII, anticorps PABP-2, anticorps PABP2, anticorps Pabp3, anticorps mPABII, anticorps ARABIDOPSIS POLY(A) BINDING 2, anticorps ATPAB2, anticorps F28A23.130, anticorps F28A23_130, anticorps POLY(A) BINDING PROTEIN 2, anticorps POLY(A)-BINDING PROTEIN 2, anticorps poly(A) binding protein 2, anticorps opmd, anticorps pab2, anticorps pabp2, anticorps pabpii, anticorps pabpn1, anticorps Pabpn1, anticorps Poly(A)-binding protein 2, anticorps fb19c03, anticorps wu:fb17e03, anticorps wu:fb18c06, anticorps wu:fb19c03, anticorps zgc:85979, anticorps zgc:92452, anticorps poly(A) binding protein nuclear 1, anticorps poly(A) binding protein, nuclear 1, anticorps poly(A) binding protein 2, anticorps poly(A) binding protein, nuclear 1 S homeolog, anticorps poly(A) binding protein, nuclear 1 L homeolog, anticorps polyadenylate-binding protein 2, anticorps poly(A) binding protein Pab2, anticorps PABPN1, anticorps Pabpn1, anticorps PAB2, anticorps pabpn1.S, anticorps pabpn1.L, anticorps LOC100728725, anticorps pab2, anticorps pabpn1
Sujet
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.Synonyms: Nuclear poly(A)-binding protein 1, PAB2, PABP-2, PABP2, Poly(A)-binding protein 2, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding protein 2
Poids moléculaire
32749 Da
ID gène
8106
NCBI Accession
NP_004634
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