PCDHa8 anticorps (C-Term)

N° du produit ABIN954036

Détail du produit anti-PCDHa8 anticorps

Antigène: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Épitope: AA 780-808, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHa8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects human PCDHA8 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region ( between 780-808 aa) of human PCDHA8.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PCDHa8

Antigène: PCDHa8 (Protocadherin alpha 8 (PCDHa8))

Autre désignation: PCDHA8 (PCDHa8 Produits)

Synonymes: anticorps PCDH-ALPHA8, anticorps protocadherin alpha 8, anticorps PCDHA8, anticorps Pcdha8

Sujet: The PCDHA8 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.Synonyms: PCDH-alpha-8, Protocadherin alpha-8

ID gène: 56140

NCBI Accession: NP_061734