PDE4B anticorps (Middle Region)
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- Antigène Voir toutes PDE4B Anticorps
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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Épitope
- AA 196-225, Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PDE4B est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes Human PDE4B (Center).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogène
- KLH conjugated synthetic peptide between 196-225 amino acids from the Central region of Human PDE4B
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PDE4B Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
- Autre désignation
- PDE4B (PDE4B Produits)
- Sujet
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: 5'-cyclic phosphodiesterase 4B, DPDE4, EC=3.1.4.17, PDE32, PDE4B, cAMP-specific 3'
- Poids moléculaire
- 83343 Da
- ID gène
- 5142
- NCBI Accession
- NP_001032416
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
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