C10orf2 anticorps (C-Term)

N° du produit ABIN954086

Détail du produit anti-C10orf2 anticorps

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Épitope: AA 663-684, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C10orf2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to PEO1.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 663-684 amino acids from the C-terminal region of human C10orf2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C10orf2

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Autre désignation: PEO1 / Twinkle (C10ORF2 Produits)

Synonymes: anticorps ATXN8, anticorps IOSCA, anticorps MTDPS7, anticorps PEO, anticorps PEO1, anticorps PEOA3, anticorps SANDO, anticorps SCA8, anticorps TWINL, anticorps C6H10orf2, anticorps D19Ertd626e, anticorps Twinl, anticorps twinkle mtDNA helicase L homeolog, anticorps twinkle mtDNA helicase, anticorps twnk.L, anticorps TWNK, anticorps Twnk

Sujet: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Synonyms: C10orf2, Progressive external ophthalmoplegia 1 protein, T7-like mitochondrial DNA helicase, Twinkle protein mitochondrial

ID gène: 56652

NCBI Accession: NP_001157284