PF4 anticorps
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- Antigène Voir toutes PF4 Anticorps
- PF4 (Platelet Factor 4 (PF4))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PF4 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is specific for Human Platelet Factor IV. AM31850PU-N (clone RTO) is seen to bind free PF4 in the absence of any bound Heparin. This is unlike AM31851PU-N (clone KKO), which binds PF4/heparin complexes to a similar degree as auto-antibodies found in individuals with Heparin-Induced Thrombocytopenia/Thrombosis (HIT/HITT).
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Protein G Chromatography of Ascitic fluid.
- Immunogène
- Human Factor IV purified from the supernatant of Thrombin activated platelets.
- Clone
- RTO
- Isotype
- IgG2b
- Top Product
- Discover our top product PF4 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- PF4 (Platelet Factor 4 (PF4))
- Autre désignation
- Platelet Factor 4 / PF4 (PF4 Produits)
- Synonymes
- anticorps CXCL4, anticorps PF-4, anticorps SCYB4, anticorps Cxcl4, anticorps Scyb4, anticorps Pf4a, anticorps RATPF4A, anticorps PF4A, anticorps CXCL4L1, anticorps CXCL4V1, anticorps PF4-ALT, anticorps SCYB4V1, anticorps PF4, anticorps platelet factor 4, anticorps platelet factor 4 variant 1, anticorps PF4, anticorps Pf4, anticorps LOC703451, anticorps PF4V1, anticorps LOC100524373, anticorps LOC102181854, anticorps LOC100630489
- Sujet
- Platelet Factor IV (PF4) is a 70 aa protein released from the alpha granules of activated platelets. PF4 is synthesized by bone marrow megakaryocytes and stored in alpha granules as a non-covalent bound tetramer. Platelet factor IV binds with high affinity to heparin and plays a role in inflammation and wound repair. PF4 is a chemoattractant for neutrophils, monocytes and fibroblasts and has been reported to be an immunologic regulator that inhibits suppressor T-cell activity.Synonyms: C-X-C motif chemokine 4, CXCL4, Iroplact, Oncostatin-A, PF-4, SCYB4
- ID gène
- 5196
- NCBI Accession
- NP_002610
- UniProt
- P02776
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